Zepbound® is available in an injectable single-dose pen and a single-dose vial, administered with a needle and a syringe. Learn about dosing, how to inject, and more.

Get patients started on once-weekly Zepbound® (tirzepatide) pen or vial, and learn more about how to use & savings options for your patients.

In combination with a reduced-calorie diet and increased physical activity: Zepbound is for adults with obesity or with overweight in the presence of at least one weight-related comorbid condition, and for adults with moderate-to-severe OSA and obesity.1 Zepbound should not be used for cosmetic weight loss.

Zepbound comes in multiple dosing forms including the Zepbound Pen and the Zepbound Vial. Learn about dosing forms for pen & vial, how to dose and helpful tips.

Zepbound ® (ZEHP-bownd) is an injectable prescription medicine that may help adults with: obesity, or some adults with overweight who also have weight-related medical problems to lose excess body weight and keep the weight off.

Learn more about the Zepbound® savings card (no Gov`t beneficiaries, terms apply), the Zepbound cash option, and LillyDirect™, an online pharmacy solutions option.

In rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. It is unknown whether Zepbound causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of tirzepatide-induced rodent thyroid C-cell tumors has not been determined.

What is Zepbound? Zepbound is an injectable prescription medicine that may help adults with obesity, or some adults with overweight who also have weight-related medical problems, to lose excess body weight and keep the weight off. Zepbound should be used with a reduced-calorie diet and increased physical activity.

Discover these resources to help guide you on your Zepbound journey including tips, guides, videos and more.

Learn more about Zepbound's® (tirzepatide) weight reduction (WR) efficacy and safety clinical data around obesity and excess weight.