Tillis, who is up for re-election next year in battleground North Carolina, voted against advancing a bill for Trump's domestic policy agenda Saturday evening.

W ASHINGTON—Centrist Sen. Thom Tillis (R., N.C.) said he won’t seek re-election in 2026, less than 24 hours after he voted against a motion to advance President Trump’s tax and spending megabill, drawing public backlash from the president.

N.C, said Sunday that he would not seek re-election, opening up a seat in a state that was already considered a battleground in the 2026 midterm elections.