Akari Therapeutics has reaffirmed its commitment to advancing research on PH1, a novel spliceosome modulator payload used in ...

Video webcast now available on-demandBOSTON and LONDON, July 22, 2025 (GLOBE NEWSWIRE) -- Akari Therapeutics, Plc (Nasdaq: ...

Splicing is a process necessary for the correct synthesis of proteins and an essential step in gene expression. An impaired ...

Spanning from the heart-stage embryo to seed germination, the study charts dynamic gene expression patterns in the embryo axis and cotyledon ...

While humans can escape the heat by seeking shade or shedding layers, plants remain rooted in place. So how do they survive ...

While humans can escape the heat by seeking shade or shedding layers, plants remain rooted in place. So how do they survive ...

While humans can escape the heat by seeking shade or shedding layers, plants remain rooted in place. So how do they survive extreme heat? It's a ...

This suggests that, in the future, small molecule inhibitors of minor spliceosome function, with favourable pharmacokinetic properties, could be developed and applied in a titratable fashion against a ...

Spliceosome structures have been investigated extensively in the past decade, but most of the studies have been restricted to a handful of model organisms. New research by Lu et al, looks outside this ...

The spliceosome is critical for the proper functioning of every cell, and numerous genetic disorders are linked to problems with spliceosome function. In most eukaryotic cells, two types of ...

Researchers unveil detailed structural insights into the minor spliceosome, shedding light on its role in gene expression and potential disease implications.