News

UroToday3d
Urge Urinary Incontinence and Pregnancy: A Systematic Review - Beyond the Abstract
Our systematic review examines urge urinary incontinence (UUI) in pregnancy. We identified several risk factors for UUI. A key finding is the literature's predominant focus on quantifying UUI symptoms ...
UroToday3d
A First-In-Human Feasibility Study of a New Implantable Tibial Nerve Stimulator for Overactive Bladder Syndrome - Beyond the Abstract
Overactive bladder (OAB) remains a prevalent and often debilitating syndrome, affecting millions worldwide. Despite numerous treatment options, including behavioral modifications, pharmacologic ...
UroToday3d
HER2, NECTIN4, and TROP-2 Expression Heterogeneity in Bladder Cancer - Expert Commentary
Muscle-invasive bladder cancer (MIBC) presents significant treatment challenges, with antibody-drug conjugates (ADCs) targeting HER2, NECTIN4, and TROP-2 emerging as promising therapeutic options.
UroToday3d
Multiomics Approach Distinguishes SPTBN4 as a Key Molecule in Diagnosis, Prognosis, and Immune Suppression of Testicular Seminomas.
Background: Testicular seminomas, a common germ cell tumor, poses clinical challenges due to its molecular heterogeneity and limited biomarkers for precise diagnosis and prognosis. Leveraging ...
UroToday3d
Preoperative prediction of WHO/ISUP grade of ccRCC using intratumoral and peritumoral habitat imaging: multicenter study.
The World Health Organization/International Society of Urological Pathology (WHO/ISUP) grading of clear cell renal cell carcinoma (ccRCC) is crucial for prognosis and ...
UroToday3d
Biochemical recurrence after radical prostatectomy and postoperative radiotherapy: current evidence and controversial issues.
This review explores challenges in managing biochemical recurrence (BCR) after radical prostatectomy and postoperative radiotherapy for prostate cancer (PCa) highlighting gaps in risk stratification, ...
UroToday3d
Early postoperative visits improve outcomes in inguinal lymph node dissection for penile cancer.
To analyse postoperative outcomes after inguinal lymph node dissection (ILND) at a high-volume North American centre for penile cancer with respect to early postoperative clinic visits facilitated by ...
UroToday3d
Phase Ib Study of Enzalutamide with Venetoclax in Patients with Metastatic Castration-Resistant Prostate Cancer.
Castration and enzalutamide induce BCL-2 to drive therapy resistance in prostate cancer (PCa). We conducted a phase Ib trial to test that metastatic castration-resistant PCa (mCRPC) can be effectively ...
UroToday4d
What Is the Role of Invasive Urodynamics in the Assessment of Male Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia.
Invasive urodynamics (iUDS) should be selectively performed in male patients with lower urinary tract symptoms before invasive treatment for benign prostatic obstruction. Recent evidence highlights ...
UroToday3d
Angiogenic and immune predictors of neoadjuvant axitinib response in renal cell carcinoma with venous tumour thrombus.
Venous tumour thrombus (VTT), where the primary tumour invades the renal vein and inferior vena cava, affects 10-15% of renal cell carcinoma (RCC) patients. Curative surgery for VTT is high-risk, but ...
UroToday3d
Prostate Cancer Foundation White Paper on Combination Therapy for Metastatic Hormone-Sensitive Prostate Cancer.
Despite several randomized controlled trials demonstrating the benefits of combination therapies for metastatic hormone-sensitive prostate cancer (mHSPC), a significant treatment gap persists. This ...
UroToday3d
Systemic Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer: ASCO Guideline Update.
To provide evidence-based recommendations for patients with metastatic castration-resistant prostate cancer (mCRPC). An Expert Panel including patient representation completed a systematic review of ...