In the Gates Foundation’s final chapter, it is doubling down on its wager that health can engender prosperity. That proposition must now contend with the mixed macroeconomic evidence.

John Ayanian is the director of the Institute for Healthcare Policy and Innovation at the University of Michigan. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal.

In patients with refractory systemic lupus erythematosus, in vivo generation of CD19 CAR T cells by means of lipid nanoparticles led to B-cell depletion, reduced disease activity, and no major toxi ...

An 11-year-old girl with eczema was evaluated for chest pain and arm pain. Imaging showed multiple bone and liver lesions. The erythrocyte sedimentation rate was higher than 130 mm per hour. A diag ...

A previously healthy 44-year-old man presented with a 4-day history of an itchy rash and a 2-day history of fever and malaise. A pleomorphic eruption of papules and pustules of different sizes and ...

To the Editor: Fetal complications in patients with hereditary thrombotic thrombocytopenic purpura (TTP) have not been reported and are currently not suspected. Fennell et al. (July 3 issue) 1 report ...

Idiopathic normal-pressure hydrocephalus is a neurologic disorder characterized by impaired gait, balance, cognition, and ...

In this phase 3, multinational, randomized, double-blind trial, we examined the safety and efficacy of once-daily orforglipron at doses of 6 mg, 12 mg, or 36 mg, as compared with placebo (assigned in ...

Tobacco use kills more than 7 million people worldwide each year, including 1.3 million who die from the effects of exposure to secondhand smoke.1 As a major contributor to cancer, cardiovascular ...

There is an urgent need for low- and middle-income countries to ensure equitable, affordable, and sustained access to tobacco-cessation medications at scale.

Amanda Janitz is an associate professor at the University of Oklahoma Health Sciences Hudson College of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the ...