The US administration has extended its line of attack on academia from US federal research to private universities. The abuse ...

Although student mobility is being restricted in a less dramatic fashion than currently in the USA, the impact on science ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...

This study highlights novel genotype-driven metabolic adaptations in PM, laying the groundwork for targeted interventions ...

MicroRNA-33a and microRNA-33b are encoded within the mammalian SREBF1 and SRBF2 genes, respectively, and both SREBF1 and ...

Phosphatidylserine (PS) is a phospholipid mainly enriched in the inner leaflet of the plasma membrane; however, its role in the nucleus remains unclear. This study describes the presence of PS in the ...

The dedifferentiation of somatic cells into a pluripotent state by cellular reprogramming coincides with a reversal of age-associated molecular hallmarks. Although transcription factor induced ...

imageimageThere are no cellular or molecular biomarkers diagnostic of myalgic encephalomyelitis (also known as chronic fatigue syndrome [ME/CFS]). We find hundreds of blood-based traits are different, ...

The spleen is a key site for extramedullary hematopoiesis that hosts a rare population of functional hematopoietic stem cells (HSCs). While the microenvironment that supports extramedullary ...

imageimageRNase H2 dissociates from shortened telomeres allowing the stabilization of RNA–DNA hybrids to drive repair. RNase H1 is subsequently recruited to telomeres to ensure the hybrids are ...

HIV-1 initiates replication by its transactivator Tat, hijacking the positive transcription elongation factor b (P-TEFb). HIV-1 infection induces liquid-liquid phase separation of LARP7, forming ...

To address a wide range of genetic diseases, genome editing tools that can achieve targeted delivery of large genes without causing double-strand breaks (DSBs) or requiring DNA templates are necessary ...