Larger studies looking at the benefits and harms of anti-TNF compared with conventional treatment for children with active Crohn's disease are needed. Among the important outcomes to be included are ...

Large studies are needed to see if targeted therapies work in the different types of IIM. As IIM is rare, this would best be done by many centres working together internationally.

Due to a lack of robust evidence, we could not determine the benefits and unwanted effects of hospital networks (organised trauma systems) or individual hospitals (designated trauma centres) that are ...

We found nine studies involving a total of 689 women with stress urinary incontinence. Nine studies compared vaginal lasers to either sham or lubricant, and one study compared vaginal lasers to ...

- Corticosteroids may decrease transient inflammatory reaction events associated with antibiotic treatment of leptospirosis infection, although the certainty of this evidence is very uncertain.

Palivizumab, when given through the veins or into a muscle (systemically), reduces hospitalisations due to respiratory syncytial virus (RSV) and reduces respiratory problems later on (chest wheezing), ...

Transcranial laser therapy (low-level light therapy applied to the head) does not reduce the number of people who die or have moderate to severe disability at 90 days after ischaemic stroke (where ...

Cochrane publishes high-quality health evidence to improve health for all. The World Health Organization, health professionals and people like you use our evidence to make informed choices about ...

Topical silver treatments and silver dressings are increasingly used for the local treatment of contaminated or infected wounds, however, there is a lack of clarity regarding the evidence for their ...

To examine whether carbamazepine or oxcarbazepine alone is an effective treatment for schizophrenia and schizoaffective psychoses and whether carbamazepine or oxcarbazepine augmentation of neuroleptic ...

Cochrane Interactive Learning is our comprehensive course on how to conduct a systematic review. Equip yourself, or your staff and students, with the skills to conduct systematic reviews through ...

Motor neuron disease, also known as amyotrophic lateral sclerosis, is a fatal neurological disease which produces paralysis of the limb, swallowing and breathing muscles. As there is no current ...