Introduction Sialorrhoea is a debilitating symptom in neurological disease and there is a growing literature for the use of intrasalivary Botulinum Toxin (botox) injections in its management. The ...

Chronic cough (CC) is common, predominantly affecting middle-aged females. Sufferers experience significantly impaired quality of life (QoL). Cough is associated with increased healthcare costs.

Rationale While cross-sectional studies have shown associations between certain occupational exposures and lower levels of lung function, there was little evidence from population-based studies with ...

1 Real World Data Science, Medical Evidence, BioPharmaceuticals Medical, AstraZeneca, Cambridge, UK 2 Respiratory Evidence Strategy, BioPharmaceuticals Medical, AstraZeneca, Cambridge, UK 3 Research ...

Introduction and Objectives The harms of hyperoxia are well recognised in COPD, with recommended peripheral oxygen saturations (SpO2) of 88–92%. Despite this, there is ongoing harm from excessive ...

Rationale Pulmonary rehabilitation (PR) is an effective, key standard treatment for people with COPD. Nevertheless, low participant uptake, insufficient attendance and high drop-out rates are reported ...

State University of New York - Health Science Center at Brooklyn & Kings County Hospital Center, Brooklyn, NY 11203, USA Correspondence to: Dr L S Efferen, Department of Medicine, Long Island Jewish ...

Rationale Advance care planning (ACP) is uncommon in patients with chronic obstructive pulmonary disease (COPD). Objectives To assess whether a nurse-led ACP-intervention can improve quality of ...

Introduction Nebulised mucolytics (hypertonic saline) and antibiotics are important therapies in the management of patients with non-CF bronchiectasis. These therapies are not without complications ...

Interstitial lung abnormalities (ILA) can be incidentally detected in patients undergoing low-dose CT screening for lung cancer. In this retrospective study, we explore the downstream impact of ILA ...

Background Prior work suggests different interstitial lung diseases (ILDs) that share the radiological usual interstitial pneumonia (UIP) pattern have an overall worse prognosis. However, ...

Climate change is altering ecosystems worldwide. While shifting environmental conditions are complex, it has been hypothesised that the impact of climate change is directly leading to increases in ...