Background Pulmonary hypertension (PH) is a progressive cardiopulmonary condition associated with increased morbidity and ...

Guidelines have been compiled by The Joint Tuberculosis Committee of the British Thoracic Society to quantify the risks of reactivation of tuberculosis with anti-tumour necrosis factor α (anti-TNF-α) ...

Background Social media may influence children and young people’s health behaviour, including cigarette and e-cigarette use. Methods We analysed data from participants aged 10–25 years in the UK ...

Background The Quality of Life-Bronchiectasis (QOL-B), a self-administered, patient-reported outcome measure assessing symptoms, functioning and health-related quality of life for patients with ...

Department of Child Health, Queen’s University of Belfast, Clinical Institute, Belfast, UK All children experience head colds and many consult their doctor because of associated coughing.1 Cough with ...

Introduction Although formal patient registries in complex home ventilation have long been recommended 1, recent review found few centres maintain accurate records of activity 2. However, the ability ...

Asthma attacks (exacerbations) are common, accounting for over 90 000 UK hospital admissions per annum. They kill nearly 1500 people per year in the UK, have significant associated direct and indirect ...

Rationale ADAM33 is an asthma susceptibility gene that plays a role in both airway remodelling and susceptibility to allergic airways disease. To study the role of ADAM33 in asthma we have exposed an ...

Correspondence to Dr John Field, Roy Castle Lung Cancer Research Programme, The University of Liverpool Cancer Research Centre, Department of Molecular and Clinical Cancer Medicine, Institute of ...

1 Division of Asthma, Allergy and Lung Biology, King's College London, London, UK 2 Department of Palliative Care, Policy and Rehabilitation, King's College London, Cicely Saunders Institute, London, ...

1 Royal Brompton & Harefield Hospitals, Guy’s and St.Thomas’ NHS Foundation Trust, London, UK Since the Guideline, there is deeper understanding of referral characteristics, outcome measures, patient ...

Introduction The PiSZ genotype results in less severe deficiency of alpha-1 antitrypsin (AAT) than PiZZ. Less is known about phenotypic and prognostic features. Methods We studied 699 PiZZ, 126 PiSZ ...