Acute respiratory distress syndrome (ARDS) is present in >10% of all people admitted to critical care and is associated with severe morbidity and mortality. Despite more than half a century since its ...

Academic Respiratory Medicine, St Bartholomew's and Royal London School of Medicine and Dentistry, St Bartholomew's Hospital, London EC1A 7BE, UK BACKGROUND Although it is presumed that exacerbations ...

2 Center for Sleep and Vigilance Disorders, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Dementia constitutes a pressing healthcare challenge. It has been estimated that by 2050, ...

Objective Reduced functional capacity and muscle weakness are two major contributors to functional impairment in chronic obstructive pulmonary disease (COPD). The underlying causes of functional ...

Background Many patients with the obstructive sleep apnoea syndrome (OSA) travel to the mountains for recreational and professional activities while temporarily discontinuing continuous positive ...

a Department of Respiratory Medicine, Sleep Laboratory and PRETA Laboratory, CHRU, Grenoble, France, b Respiratory Department, Bristol Royal Infirmary, Bristol, UK Professor PA Levy, EFCR, Pneumologie ...

Background The aetiology of acute exacerbations of COPD (AECOPD) is incompletely understood. Understanding the relationship between chronic bacterial airway infection and viral exposure may explain ...

Introduction and objectives Non-invasive ventilation (NIV) has been shown to reduce in-patient mortality in AECOPD from 20 to 10%. In 2011 national data revealed that there were multifactorial ...

Background: Rhinovirus infection is responsible for considerable morbidity and mortality as the major cause of exacerbations of asthma, and is also known to induce exacerbations of cystic fibrosis and ...

Background Previous studies have reported an association between weight increase and excess lung function decline in young adults followed for short periods. We aimed to estimate lung function ...

Associations of pulmonary microvascular blood volume with per cent emphysema and CT emphysema subtypes in the community: the MESA Lung study ...

aRespiratory Medicine, Imperial College School of Medicine, National Heart and Lung Institute, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK, bCancer and Blood Programme, The Hospital for ...