gut.bmj

The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications

4 Department of Hepatogastroenterology, Hopital Claude Huriez, CHRU Lille, France Correspondence to: Professor J-F Colombel Department of Hepato-Gastroenterology, Hopital Claude Huriez, CHRU de Lille, ...
gut.bmj

Deep mural injury and perforation after colonic endoscopic mucosal resection: a new classification and analysis of risk factors

Objectives Perforation is the most serious complication associated with endoscopic mucosal resection (EMR). We propose a new classification for the appearance and integrity of the muscularis propria ...
gut.bmj

Epidemiology of chronic liver diseases in the USA in the past three decades

Objective Given significant advances in treatment of viral hepatitis and the growing epidemic of obesity, the burden of the different types of liver diseases in the USA may be changing. Our aim was to ...
gut.bmj

Vedolizumab affects antibody responses to immunisation selectively in the gastrointestinal tract: randomised controlled trial results

Correspondence to Dr Tim Wyant, Takeda Pharmaceuticals International Co, 40 Landsdowne St, Cambridge, MA 02139, USA; Tim.Wyant{at}takeda.com Design In this randomised, double-blind, placebo-controlled ...
gut.bmj

Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFα therapy

Background Anti-tumour necrosis factor α (TNFα) therapy effectively induces and maintains remission in Crohn's disease (CD). Up to 40% of patients, however, fail to respond to anti-TNFα. Objective To ...
gut.bmj

Increased expression of interleukin 17 in inflammatory bowel disease

Department of Internal Medicine, Shiga University of Medical Science, Seta-Tukinowa, Otsu 520-2192, Japan Correspondence to: Dr A Andoh, Department of Internal Medicine, Shiga University of Medical ...
gut.bmj

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

Objective Pancreatic ductal adenocarcinoma (PDA) is characterised by stromal desmoplasia and vascular dysfunction, which critically impair drug delivery. This study examines the role of an abundant ...
gut.bmj

Long-term safety of infliximab for the treatment of inflammatory bowel disease: a single-centre cohort study

ProfessorDr P Rutgeerts, Internal Medicine, Department of Gastroenterology, Herestraat 49, B-3000 Leuven, Belgium; Paul.Rutgeerts{at}uz.kuleuven.ac.be Background and aims: This study evaluates the ...
Gut

AI-empowered human microbiome research

Recent advances in high-throughput microbiome profiling have generated expansive data sets that offer unprecedented ...
gut.bmj

Alleviated T cell exhaustion and SLC1A3-mediated stroma-remodelling dictate chemoimmunotherapy efficacy in oesophageal squamous cell carcinoma

3 Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Chinese Academy of Medical Sciences, Peking Union Medical College, ...
gut.bmj

Treatment of chronic erosive gastritis with prednisolone.

Short-term oral prednisolone was successfully used in the treatment of four patients with chronic erosive gastritis which had failed to respond to conventional therapies. Symptomatic improvement ...
gut.bmj

Differentiating gastroparesis from functional dyspepsia is no longer sufficient

We read with interest the commentary by Camilleri and Talley on whether gastroparesis and functional dyspepsia (FD) are ‘really ‘interchangeable’ diseases’. 1 Their significant efforts to improve the ...