Journal clubs, typically involving a group of health professionals or trainees who discuss recent study findings, have long ...

MetaImpact. To design a new trial based on the prospective updated meta-analysis, Sutton et al5 propose a hybrid frequentist–Bayesian approach using simulations. New studies of a user-defined size are ...

Evaluating methodological quality. Pierson7 provided an approach to evaluate the validity of a case report based on five components: documentation, uniqueness, objectivity, interpretation and ...

Computational methods can contribute to evidence management with automation of literature searching, critical appraisal and guidelines.4 5 Similarly, big data already contribute to aetiological, ...

Introduction. The concepts of evidence-based medicine are evolving as limitations of early models are addressed. In this editorial, we present a new model for evidence-based clinical decision making ...

Alcohol-based hand sanitisers, if ingested, can have toxic effects and may even be lethal. Preventable deaths from ingesting hand sanitisers have been identified. This article describes two Prevent ...

Commentary on: Callen JL, Westbrook JI, Georgiou A, et al. Failure to follow-up test results for ambulatory patients: a systematic review. J Gen Intern Med 2012; 27: 1334– 48.[OpenUrl][1][CrossRef][2] ...

Objectives To describe the proportion of transvaginal ultrasounds performed in a University Hospital of Buenos Aires (Argentina), requested upon a health check. Method Cross-sectional study of a ...

A recent UK trial addressed whether routine use of fluoxetine in patients who had a stroke improved motor recovery at 6 months. ### EBM Verdict EBM Verdict on: Effects of fluoxetine on functional ...

Conclusions Increased end-user participation in peer review appears to be associated with strong research accessibility, replicability, and relevance, as measured by research impact, readership, ...

Objectives Failure to recognise and respond to patient deterioration in an appropriate and timely manner has been highlighted as a global patient safety concern. Early Warning Scores (EWSs) using ...

Context. The Apgar score was originally intended to assess the condition of the newborn 1 min after birth, predict survival and to compare methods of resuscitation, various obstetric and anaesthetic ...