Objectives Pica is a problematic and little-studied health concern in children with sickle cell disease, defined as the age-inappropriate consumption of non-nutritive materials. 1 Pica behaviours can ...

BACKGROUND Cause specific research on death certification in chronic disease has rarely involved cerebral palsy. AIMS To evaluate cause of death information in people known to have cerebral palsy by: ...

Correspondence to Dr Mary E Ramsay, Department of Immunisation, Hepatitis and Blood Safety, Public Health England, 61 Colindale Avenue, London NW9 5EQ, UK; Mary.ramsay{at}phe.gov.uk By 2010, the ...

Objective To evaluate the efficacy differentials among corticosteroid regimens by type, dosage and duration, we conducted a systematic review and network meta-analysis of randomised controlled trials ...

Clinical, immunological, and intestinal studies on 26 children with IgA deficiency in the age range 2 to 16 years are reported. 9 of these children were suffering from autoimmune disease, namely ...

1 Paediatric Liver, Gastroenterology & Nutrition Centre and MowatLabs, King’s College Hospital NHS Foundation Trust, London, UK Portal hypertension (PHT), defined as raised intravascular pressure in ...

The hierarchy of evidence in assessing the effectiveness of interventions or treatments is explained, and the gold standard for evaluating the effectiveness of interventions, the randomised controlled ...

Rett syndrome is a severe neurodevelopmental disorder of unknown aetiology. A prolonged QT interval has been described previously in patients with Rett syndrome. To investigate QT prolongation and the ...

1 Department of Women's and Children's Health, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand Correspondence to Dr Rachel Y Moon, Division of General Pediatrics and Community ...

Clear sex differences exist in asthma and atopy with a preponderance of boys before puberty. There is a reversal of this sex ratio during puberty with girls having more asthma and atopy throughout the ...

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Estimates for the UK suggest that alcohol consumption during pregnancy and prevalence of fetal alcohol spectrum disorder (FASD)—the most common neurodevelopmental condition—are high. Considering the ...