IVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA.

The radiation emitted by high-resolution cryo-EM instruments can damage proteins. And some parts of proteins can be harmed more than others, complicating imaging. To reduce radiation damage and ...

S ample loss has been a persistent problem in cryo-EM, a high-tech method for creating 3D models of molecules that reveal their inner structures. It occurs during an essential step of imaging ...

The increasingly mainstream technique called cryo-electron microscopy, or cryo-EM, may be used to investigate the high-resolution structures of biomolecules—and discern how biomolecules interact ...

Although initially X-ray crystallography was commonly used, the much more versatile EM is now the standard approach in the form of cryo-EM, with recent advances giving us unprecedented looks at ...

A team of biochemists devised a solution that makes it possible to hold small protein molecules in place while they're being imaged, which will enable cryo-EM to produce much clearer images of ...

or cryo-EM. The technology was revolutionary because it enabled scientists to see the atomic structure of biological molecules in high resolution. But cryo-EM still had a catch: It was only effective ...

Overall structure of a transmembrane ZIP zinc transporter protein determined by cryo-electron microscopy (cryo-EM) (left) and a schematic showing some of the functional features (right).

Cryo-EM is rapidly becoming the method of choice for structural biologists and biochemists around the world, helping these scientists accelerate their research and expand their analytical capabilities ...

Get Instant Summarized Text (Gist) A magnetic bead-based method, MagIC cryo-EM, reduces sample loss during cryo-EM preparation by up to 1,000-fold, enabling imaging of rare or hard-to-purify ...