Zebrafish have the remarkable and rare ability to regrow and repair their hearts after damage. New research from Caltech and ...

When a zebrafish heart is damaged, it can fully restore its function within 60 days. ... However, the gene for Hmga1 is present in humans and active during embryonic development.

Developing zebrafish offer a convenient model for studying the heart because they are transparent, grow quickly—developing a heartbeat in only 24 hours—and can be imaged by the dozen.

Zebrafish heart 60 days after injury showing the structure of the heart muscle cells have completely regenerated. [Phong Nguyen, copyright Hubrecht Institute.] Researchers from the group of Jeroen ...

The team then compared the activity of the Hmga1 gene in zebrafish, mice, and humans. In human hearts, as in adult mice, the Hmga1 protein is not produced after a heart attack.

Unlike humans, zebrafish can completely regenerate their hearts after injury. They owe this ability to the interaction between their nervous and immune systems, as researchers led by Suphansa ...

They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. ... However, the gene for Hmga1 ...

They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. ... However, the gene for Hmga1 is present in humans and active during embryonic development.

Researchers from the Bakkers group at the Hubrecht Institute have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in ...