Cochrane says that guidance on the use of both neuraminidase inhibitors Tamiflu (oseltamivir) and GSK's Relenza (zanamivir) to prevent or treat flu should be revised to take account of the ...

Context The neuraminidase inhibitor zanamivir, administered as an inhaled powder, is approved for the prevention and treatment of influenza in adults and children older than 7 years. Previous ...

We have identified a virus, B/Perth/211/2001, with a spontaneous mutation, D197E in the neuraminidase (NA), which confers cross-resistance to all NA inhibitors. We analyzed enzyme properties of the ...

BCX-1812 (RWJ-270201): Discovery of a Novel, Highly Potent, Orally Active, and Selective Influenza Neuraminidase Inhibitor through Structure-Based Drug Design Y. Sudhakar Babu , Pooran Chand , Shanta ...