Scientists pave way to stopping aggressive cancers before they spread - The discovery could pave the way for treatments to ...

Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical ...

New research has uncovered a complex interplay between extracellular matrix (ECM) structure and the transcriptional responses ...

Physiological extracellular matrix (ECM) calcification or mineralization is restricted to bones, teeth and the hypertrophic zone of growth plate cartilage. In contrast, pathological ECM ...

Scientists have developed Rhobo6, a light microscopy probe that reveals extracellular matrix structures in live tissues, ...

Fascia of live mouse pancreas, in which the extracellular matrix is labeled with Rhobo6 (red) and nuclei are labeled with ...

Our group has explored the regeneration of soft biological tissues through cell-extracellular matrix interactions, with a focus on collagen-rich environments and fibrosis. We have developed a new ...

Researchers have developed a regenerative medicine method that successfully grafts myoblasts onto healthy muscle, boosting ...

We show here that extracellular matrix proteins interact with soluble CD95L and potentiate its pro-apoptotic activity. The cytotoxicity of supernatants from CD95L-expressing cells was increased by ...

Scientists have discovered a new way to predict which cancer tumours will become aggressive before they spread – paving the ...

So far, Fiore's new direction is paying off. The extracellular matrix supports and gives structure to our cells and tissues: It provides a scaffold for cells to grow in, dictates the mechanical ...