The findings in animals may help advance treatment options for dry age-related macular degeneration (AMD), which ... One graft consisted of retinal pigment epithelial (RPE) cells grown on a ...

Reference: Sudharsan R, Murgiano L, Ahuja A, et al. Novel photoreceptor-specific promoters for gene therapy in mid-to-late stage retinal degeneration. Mol Ther. doi: 10.1016/j.ymthe.2025.05.020 This ...

Millions of people suffer from retinal disorders, such as macular degeneration and retinitis pigmentosa. A new study suggests that injecting gold nanoparticles into the retina and stimulating ...

A new study suggests that injecting gold nanoparticles into the retina and stimulating those particles with lasers could restore partial vision for these patients. The gold nanoparticles, excited ...

Photoreceptor outer segments (POS) are essential for vision, and their dysfunction is associated with retinal degeneration and subsequent vision loss. Retinal organoids (ROs) have emerged as a ...

Greenland sharks, the longest-lived vertebrates in the world, show no signs of physical deterioration in their retinas even after living for hundreds of years. The finding is especially surprising ...

In this rat model of retinal degeneration, subretinal administration of OPGx-MERTK (1E10 vg/eye) demonstrated effective preservation of both photoreceptors and retinal function. OPGx-MERTK (AAV2 ...