Certain DNA sequences can form structures other than the canonical double helix. These alternative ... the genome to go beyond sequence to include structure. "We hope our study will serve as ...

Abstract: DNA triple helix structure, as a highly specific gene targeting tool, enable gene regulation by precisely identifying and binding to target DNA sequences. However, the limits of design ...

More than seven decades later, mathematician Robert Monjo believes he has discovered a similarly significant double helix — but this time not as the structure of human DNA, but as the structure ...

This model has become known as the Triple Helix Model, as it combines three key stakeholders woven together to create the ‘DNA’ of scientific innovation ... with linkages influenced by decentralized ...

The structure described here contains ... The results presented here will allow better assessment of triple helix-forming propensities of DNA repeat sequences. They are also of value for the ...

A triple-helix DNA structure can form when certain nucleobases – pyrimidine or purine – occupy the major grooves in conventional B-DNA. This can happen naturally or as part of intentional ...

The competition led to some notable misfires, such as Linus Pauling’s triple helix. In 1953 ... understanding DNA’s structure “raised the possibility of reading, synthesizing, duplicating ...

Rosalind Franklin’s role in the discovery of the structure of DNA may have been ... papers announcing the discovery of DNA’s double helix was published. Watson, Crick and Wilkins won the ...

Originally published in Nature on 25 April 1953, taken from The double helix and the ‘wronged heroine ... of some proteins and published a paper suggesting a triple-helical structure of DNA. Racing to ...