University of South Alabama researchers report that neurons can transfer mitochondria directly to cancer cells, enhancing their metastatic potential.

We demonstrate that increasing oxygen availability reprogrammed cells away from glycolytic and toward oxidative metabolism, increased pyruvate dehydrogenase (PDH) flux, tricarboxylic acid (TCA) cycle ...

6-PPD quinone at environmentally relevant concentrations disrupts citric acid cycle in Caenorhabditis elegans: Role of reduction in acetyl CoA and pyruvate contents ...

Specifically, we examine the tricarboxylic acid cycle (also known as TCA, Krebs cycle, or citric acid cycle) and a plausible precursor prebiotic network of reactions leading to the TCA cycle.

Results RV‐PA coupling was negatively associated with tricarboxylic acid (TCA) cycle intermediate levels. Specifically, plasma α‐ketoglutarate and fumarate were significantly associated with all ...

The chemistry of cold molecular clouds is remarkably rich in complex organic molecules. By replicating the conditions of ice-coated nanoparticles in these cold regions of space, laboratory simulation ...

The complete tricarboxylic acid (TCA) cycle, comprising a series of 8 oxidative reactions, occurs in most eukaryotes in the mitochondria and in many prokaryotes. The net outcome of these 8 chemical ...

Considering the central roles of glycolysis, the tricarboxylic acid cycle (TCAC), and oxidative phosphorylation (OXPHOS) in cellular metabolism, which bridge catabolism and anabolism, changes in the ...