Food allergies can be life-threatening due to the rapid and exaggerated immune response. While mucosal mast cells (MMCs) are ...

Topical corticosteroids are still a mainstay of treatment for atopic dermatitis ... which then crosslinks preformed drug-specific IgE on mast cells, activating a cascade for allergic reaction.

This inspired our research team to investigate the role of mucosal mast cells in the pathogenesis of food allergy." Initially, the researchers generated an IgE-mediated food allergy model using ...

Mucosal mast cells are immune cells that arise from bone marrow and play a key role in the sudden onset of food allergy symptoms ...