COP, cryptogenic organizing pneumonia; CT, computed tomography; GGO, ground-glass opacities; T-DXd, trastuzumab deruxtecan. Fig 2. COP pattern of pneumonitis in a 76-year-old woman with breast cancer ...

Trastuzumab deruxtecan plus pertuzumab demonstrated statistically and clinically significant improvement in progression-free ...

They noted 10.5% of patients in the trastuzumab deruxtecan group experienced adjudicated drug-related interstitial lung disease or pneumonitis vs. 1.9% in the trastuzumab emtansine group — none ...

A total of 12 patients had trastuzumab deruxtecan–related interstitial lung disease or pneumonitis (grade 1 or 2 in 9 patients and grade 3 or 4 in 3), as adjudicated by an independent committee.

A higher percentage of patients assigned trastuzumab deruxtecan experienced interstitial lung disease/pneumonitis (15.2% vs. 3.1%); however, cases were mild or moderate, Hurvitz said.

Trastuzumab deruxtecan belongs to a group of antineoplastic drugs known as antibody-drug conjugates (ADCs). This type of treatment combines two therapies into one.

WILMINGTON, Del.--(BUSINESS WIRE)--High-level results from the primary analysis of the ongoing DESTINY-PanTumor02 Phase II trial showed ENHERTU ® (fam-trastuzumab deruxtecan-nxki) demonstrated ...

--(BUSINESS WIRE)-- Positive high-level results from a planned interim analysis of the DESTINY-Breast09 Phase III trial showed ENHERTU® (fam-trastuzumab deruxtecan-nxki) in combination with ...

Patterns of Treatment Failure After Selective Rearranged During Transfection (RET) Inhibitors in Patients With Metastatic Medullary Thyroid Carcinoma Ninety patients with advanced cancers who ...