The generation of multiple microenvironments in the thymus, such as the cortex and the medulla, requires crosstalk signals from developing thymocytes. Lympho–stromal interactions in multiple ...

Figure 3: Medulla–cortex re-organization after implantation of thymus epithelial grafts in vivo. Figure 4: Medullary islets arise in thymus stromal cell grafts generated from two different donor ...

The thymus is roughly divided into two main regions, the medulla and the cortex. It has previously been unclear whether the cortex is involved in negative selection, or whether this process is ...

was able to show how the ratio of compartments in the thymus - known as the cortex and the medulla - changes with age. The researchers showed that structures called Hassall's bodies appear early ...