A harmful form of the tau protein, which builds up in Alzheimer’s disease and similar brain disorders, can directly damage blood vessels in the brain, according to a new study by researchers at ...

Clinical trials to test vaccine against Alzheimer's-promoting tau protein. ScienceDaily. Retrieved June 11, 2025 from www.sciencedaily.com / releases / 2025 / 04 / 250423164249.htm.

The study also showed that female participants may be more at risk of a heavier buildup of tau protein than male participants. "We were surprised to see that people with a father with Alzheimer's ...

New data presented at AD/PD™ 2023 show Biogen’s BIIB080 (MAPT ASO) substantially reduced tau protein levels in patients with early-stage Alzheimer’s disease. News release. Biogen. March 29 ...

--Biogen Inc. today announced that the U.S. Food and Drug Administration has granted Fast Track designation to BIIB080, an investigational antisense oligonucleotide therapy targeting tau, for the ...

Biogen’s Investigational Tau-Targeting Therapy BIIB080 Receives FDA Fast Track Designation for the Treatment of Alzheimer’s Disease Provided by GlobeNewswire Apr 2, 2025, 11:30:00 AM ...

Tau tangles typically form years after the formation of another protein called amyloid, which creates plaques in the brain and is one of the first hallmarks of Alzheimer’s. The greater the ...

The neurotransmitter glutamate is essential for regulating everything from mood to memory, but it can also encourage a toxic buildup of protein, which can contribute to Alzheimer’s and ...

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease. Using human induced pluripotent stem cells (iPSCs) ...

The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC-derived neurons to amyloid beta and phosphorylated tau-induced neuronal dysfunction. Alzheimer's & Dementia, 2025 DOI: 10. ...

Phosphorylated tau 217 better detected Alzheimer’s disease pathology across a range of neurodegenerative syndromes compared with other plasma blood-based biomarkers, data from a study in JAMA ...