A new role of genes that have an important influence on the development and progression of liver cancer has been revealed by ...

DNMT3A mutations emerged as potential biomarkers for enhanced immunotherapy benefit in non-small cell lung cancer.

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

Can the TCGA bulk RNA-seq data be dissected using only macrophage subsets ? #109. Copy link. Description. gloriafight. opened on Jan 10, 2025. Issue body actions. If I only had single-cell RNAseq data ...

The scores for these biological processes were computed using RNA-seq data from the TCGA database, and the median score was used as a cut-off to categorize patients into different groups. Out of the ...

To download the The Cancer Genome Atlas (TCGA)-BLCA data, we used the TCGAbiolinks (version 2.28.0) R package and retrieved the normalized expression RNA-seq data for bladder patients from the ...

Processed RNA sequencing data on the IMvigor210 cohort were downloaded from IMvigor210CoreBiologies, 14 a fully documented software and data package for the R statistical computing environment, 18 and ...

Although distinct RNA modification-related regulator clusters and regulator gene subtypes were identified, the analysis was limited within the TCGA-SARC cohort. We further built the RNA regulator ...