The full lupus nephritis guideline includes 28 graded recommendations and 13 ungraded good practice statements. On May 7, 2025, the American College of Rheumatology (ACR) released the full guideline ...

Extrarenal lupus flares continue to occur in more than one-third of patients with end-stage kidney disease (ESKD) receiving renal replacement therapy (RRT), investigators report. Flare risk is higher ...

Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. It affects both men and women, with a female predominance. On the other hand, many different studies have showed that ...

Lupus is a chronic autoimmune disease with a long list of symptoms that affect the skin. Hives (urticaria) are a rash that can be intensely itchy. The type involved in lupus typically lasts for more ...

Systemic lupus erythematosus (SLE) can have links with sleep disorders such as insomnia and obstructive sleep apnea. Lupus can also make you wake up more in the night. If lupus is affecting the ...

Lupus symptoms tend to increase (flare up) and reduce (remit) over time. Diagnosis tends to be challenging because the symptoms look like those of other diseases. There is no specific test for lupus, ...

About Systemic Lupus Erythematosus Systemic lupus erythematosus (SLE) is an incurable chronic autoimmune disease marked by systemic inflammation that affects multiple organ systems including the skin, ...

For inclusion, all had to have a Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) of four or more for clinical manifestations, have been treated with at least two prior disease ...

Lee I, Zickuhr L, Hassman L. Update on ophthalmic manifestations of systemic lupus erythematosus: Pathogenesis and precision medicine. Curr Opin Ophthalmol. (2021) 32:583–9. doi: ...

The symptoms of SLE can range from mild to life-threatening and often include fatigue, joint pain, rash, and fever. SLE impacts approximately 1.5 million people in the United States.