The Mona Lisa has been vandalized five times with the first known-time dating all the way back to 1956 and the most recent being in 2022. In 1956, the Mona Lisa was attacked not once, but twice.

Mona Lisa, also called 'La Gioconda' or 'La Joconde', c1503-1506. Oil on wood by Leonardo da Vinci. UniversalImagesGroup/Getty ...

Then You Probably Are Too, New Research Says If you see the painting in a bad mood, it might look very different. Leonardo da Vinci, Mona Lisa (c. 1503–06). Courtesy of the Louvre, Paris.