Steroid biosynthesis ... some other groups of lipid transporters by their high degree of specificity. By mapping the aligned START domain sequences onto the crystal structure, we can now begin ...

For small-molecule drug development, the initial lead structure may be derived from modifications of the natural bioactive lipid (for example, using a steroid core, conformationally restricting a ...

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. A team led by ...

The findings have been published in Communications Chemistry. Lipid nanoparticles (LNPs) came to prominence for the delivery of RNA with the success of the Moderna and Pfizer BioNTech COVID-19 ...

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. A team led ...

A recent Phase 3 clinical trial demonstrated that a steroid-free topical foam, roflumilast (Zoryve), significantly improved the signs and symptoms of psoriasis on both the scalp and body.

Pfizer and BioNTech licensed an ionizable lipid called ALC-0315 from Acuitas. Those ionizable lipids, which are remarkably similar in structure, were discovered while the firms were optimizing ...

LPD-3 was resolved as a 345-angstrom elongated tunnel-like structure with a hydrophobic interior filled by 27 lipid molecules and three additional phospholipids within its transmembrane domain.

OpenAI, in which Microsoft has invested more than $13 billion, outlined plans in December to convert its for-profit arm into a public benefit corporation, a structure designed to balance ...

While “Let it rip” may be the public-facing energy Quinn brings on Sundays, behind the scenes, he’s building up his coaching staff with a deliberate structure and one conversation at a time.

Johnson's steroid use was exposed in late 2022, when leaked emails revealed that he was paying upwards of $11,000 a month for massive doses of Omnitrope, a pharmacy-grade HGH supplement ...