In order to assess luciferase activity in hematopoietic stem cells (HSCs) derived from UbC6-Luc mice, recipient C57BL/6-TyrC mice (Jackson Labs, Bar Harbor, ME, USA) were irradiated with a split d ...
Then, these isolates could be clonally expanded to produce an isogenic cell population. We conclude that this split luciferase probe should be a broadly useful platform for many live cell DNA ...
Modulation of Protein–Protein Interactions with Molecular Glues in a Synthetic Condensate Platform
Split luciferase complementation via stabilization of the 14-3-3γ/ERRγ PPI also correlated strongly with the stabilization factor determined for the dynamic covalent molecular glues, as determined by ...
Other split-luciferase systems such as the NanoLuc-based NanoBiT system are also reversible and can even report recruitment without receptor modification (Janetzko et al., 2022) but can only report on ...
As big supporters of smart training, Women's Health know that structuring your exercise is essential to seeing and feeling results, and a 3-, 4-, or 5-day workout split is a no-brainer.
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Elevated cortisol in chronic stress and mood ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The DNA-damaging agent Gemcitabine (GEM) is a ...
The manuscript represents a fundamental advance in designing peptide inhibitors targeting Cdc20, a key activator and substrate-recognition subunit of the APC/C ubiquitin ligase. Supported by ...
Split Fiction is the newest game coming from Hazelight Studios, the minds behind the revolutionary co-op title It Takes Two and it's releasing in a few weeks! That's right, after making the go-to ...
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