A popular solution is to use a garage floor coating like Rust-Oleum Epoxyshield. These products seal the concrete so chemicals can't penetrate it and leave a smooth, easy-to-clean surface.

Q: I am considering using rubber or PVC tile for my garage floor. In a column last year, you mentioned several brands. Several of those have the “mushroom” style tabs, and I think that these ...

Make sure the floor is free of wax or grease and, as the final step in preparation, scuff the surface of the tiles with 80-grit sandpaper to provide a grip for the adhesive, and vacuum up all dust.