Article Reference: Shi-Bing Zhang, Ming Hong and Xiao-Yang Sun et al. Silybin has therapeutic efficacy against non-small cell lung cancer through targeting of Skp2. Acta Materia Medica. Vol. 1 (3 ...

Background: p45 S phase kinase-associated protein-2 (p45 skp2), a member of the F-box family of proteins, is an important component of the Skp1-Cullin-F-box protein (SCF) ubiquitin-ligase complex (SCF ...