Intracellular signalling peptides and proteins are peptides and proteins involved in transmission of signals (signal transduction) across the membrane of cells. Signals in the form of second ...

Signal Transduction; Membrane Dynamics and Lipid Signaling; ... Lipid transfer proteins: Proteins that mediate the movement of lipid molecules between membranes, often utilising specialised domains.

The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...

Mutations in EGLN1, the gene encoding for hypoxia-inducible factor (HIF) prolyl-4-hydroxylase 2 (PHD2), cause erythrocytosis and in rare cases the development of neuroendocrine tumors. In the presence ...

This is a valuable and rigorous study that addresses the question of what determines the spatial organization of endocytic zones at synapses. The authors use compelling approaches, in both Drosophila ...