Usually, the 49ers have been facing the Seahawks in Seattle in primetime lately. Week 1 in 2025 puts an end to it, and it's likely because the Seahawks aren't expected to be that entertaining.

On the flip side, the Seahawks beat the 49ers on the road four straight from 2014-2017, the Arizona Cardinals from 2021-2024 (and counting, hopefully), and the St. Louis Rams five straight from ...

Both the Rams and Seahawks beat the 49ers, but LA beat them twice, so that counts as two wins compared to just one for Seattle. Here is a recap of those teams and when they play: — Denver at ...

Seattle Seahawks head coach Mike Macdonald looks on during the second quarter of the game against the San Francisco 49ers at Lumen Field, on Thursday, Oct. 10, 2024, in Seattle, Wash. Brian Hayes ...

The over/under for the game was set at 45.5 points. Last season, the 49ers defeated the Seahawks, 36-24, in Week 6. Seattle later defeated San Francisco, 20-17, during Week 11.

Usually, the 49ers have been facing the Seahawks in Seattle in primetime lately. Week 1 in 2025 puts an end to it, and it's likely because the Seahawks aren't expected to be that entertaining.

Both the Rams and Seahawks beat the 49ers, but L.A. beat them twice, so that counts as two wins compared to just one for Seattle. Most Read Sports Stories.

Usually, the 49ers have been facing the Seahawks in Seattle in primetime lately. Week 1 in 2025 puts an end to it, and it's likely because the Seahawks aren't expected to be that entertaining.