Background SLE is a systemic autoimmune disease with a large number of common risk gene variants, but several rare gene ...

Agents such as azathioprine, methotrexate and cyclosporine A have been used for several decades in the management of SLE, but the evidence for their efficacy in nonrenal lupus has remained limited.

The Assessment of SpondyloArthritis International Society has recently developed new criteria for classification of both axial and peripheral SpA. The new criteria were formulated with the aim of ...

July 10, 2024 — Scientists have discovered a molecular defect that promotes the pathologic immune response in systemic lupus erythematosus (known as lupus) and show that reversing this defect ...

Abstract Research of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia (FM), two acquired chronic illnesses affecting mainly females, has failed to ascertain their frequent ...

Obinutuzumab, a humanized type II anti-CD20 monoclonal antibody, provided significantly better renal responses than placebo in a phase 2 trial involving patients with lupus nephritis receiving ...

Lupus involves unpredictable symptom flares and potential changes in brain chemistry that may increase your risk of experiencing depression and anxiety. Lupus is a chronic (long-term) autoimmune ...

41 St. Joseph's Health Care London and University of Western Ontario, London, Ontario, Canada Objective The 1980 American College of Rheumatology (ACR) classification criteria for systemic sclerosis ...

Robust nomenclature reduces diagnostic delay. However, key aspects of current nomenclature are widely perceived to be out of date, these include disease definitions, classification and diagnostic ...

Among the total systemic sclerosis cohort, 14% of individuals were categorized as frail and 53% as prefrail, with frailty status linked to an increased risk for mortality.