The Ras homolog gene family member A/ROCK pathway plays an important role in various fundamental cellular functions, including contraction, motility, proliferation, and apoptosis, whereas its ...

1 Department of Nephrology, The Second Xiangya Hospital, Central South University, Changsha, China 2 Hunan Key Laboratory of Kidney Disease and Blood Purification, Changsha, China The kidney is an ...

Department of Oncology, Clinical and Basic Research Team of TCM Prevention and Treatment of NSCLC, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangdong Provincial ...

Thereafter, a series of studies demonstrated the important roles of Rho-kinase in the cardiovascular system. The RhoA/Rho-kinase pathway is now widely known to play important roles in many cellular ...

we hope to integrate recent data within a broader picture of the biology of mechanotransduction. Two main factors contribute to the mechanical stresses that are experienced by cells and influence ...

In recent years, the TGF-β signaling pathway and miRNAs have played important roles in the pathogenesis of PH. TGF-β regulates the proliferation, migration and fibrosis of vascular smooth muscle cells ...

College of Pharmacy, Jouf University, Sakaka, Aljouf 2014, Saudi Arabia ...