The retinoid X receptor (RXR), a member of the nuclear-receptor superfamily, is a common binding partner for a subgroup of other nuclear receptors. The resulting functional complex of one RXR ...

Retinoid X receptors (RXRs ... acid receptor (RAR), vitamin D receptor (VDR), thyroid receptor, liver X receptor (LXR), peroxisome proliferator-activated receptor (PPAR), pregnane X receptor ...

vitamin D 3 receptor and pregnane X receptor, and permissive partners like peroxisome proliferator-activated receptors (PPARs) α, β/δ, and γ, the farnesoid X receptor (FXR) and liver X ...

A regulator of gene expression, retinoid X receptor (RXR), can boost scavenging cells in their mission to clear the brain of dead cells and debris after a stroke, thus limiting inflammation and ...

Retinoids and retinoid analogues exert their activities by interacting with nuclear receptors (RARs [retinoic acid receptors] or RXRs [retinoic X receptors ... retinoic acid receptor RAR β ...

Boosting NMDA receptor signaling corrected excess protein synthesis in Fragile X model mice. Experimental drug Glyx-13 restored synaptic plasticity and reduced seizures in mice. Findings open the door ...

A nuclear receptor protein called retinoid X receptor gamma (RXRgamma) is known to promote OPC differentiation and remyelination, but, because nuclear receptors generally function in pairs ...

As the incidence of type 2 diabetes increases, new treatments are clearly needed. Many hormones and drugs that control metabolic pathways function as agonists or antagonists of nuclear receptors ...