It blocks a protein that binds to a form of vitamin A (retinoic acid) in our cells, known as retinoic acid receptor alpha (RAR-α).

With nearly half of all pregnancies worldwide being unintended, the need for effective, reversible male contraceptives remains urgent. Despite decades of research, men still have very few birth ...

Given the importance of pyrimidine synthesis in malignant transformation and the fact that this process is typically non-essential for most mammalian tissues’ homeostasis, de novo pathway enzymes ...

Discover dermatologist-approved ways to build collagen in your skin and learn which collagen tips actually work for firmer, ...

Biochar stands out as an excellent carrier for low-temperature SCR catalysts, but its synthesis is often time-consuming and requires high temperatures and fossil fuels. Therefore, sustainable and ...

An efficient base-catalyzed method for the methylenation of imidazo [1,2- a]pyridines using glyoxylic acid was discovered. Various imidazo [1,2- a]pyridines were successfully converted to bis (imidazo ...

Retinoic acid stops uncontrolled cell growth in laboratory cell cultures and might reduce the return of the tumour after high-dose chemotherapy followed by autologous haematopoietic stem cell ...