Researchers demonstrated that systemic factors from young mice can rejuvenate the aging retina by alleviating cellular senescence and restoring function.

The discovery of the full structure of RBP3 and its conformational plasticity opens a new chapter in research on the functioning of the visual cycle and the mechanisms leading to retinal degeneration.

Improvement of OPL structure, maintaining input from photoreceptors. ROS levels were reduced by up to 50% , and no mortality occurred in any Telomir-1 treatment group.

More information: Raghavi Sudharsan et al, Novel Photoreceptor-Specific Promoters for Gene Therapy in Mid-to-Late Stage Retinal Degeneration, Molecular Therapy (2025). DOI: 10.1016/j.ymthe.2025.05.020 ...

The research represents significant progress in understanding how the proteome may change in different retinal dystrophies. Published in Molecular & Cellular Proteomics, the study was carried out ...

How neurons build a 3-D vascular structure to keep the retina healthy Date: May 24, 2024 Source: University of California - San Francisco Summary: Scientists have known for years that a lattice of ...