SAMETA: An open-label, three-arm, multicenter, phase III study of savolitinib + durvalumab versus sunitinib and durvalumab monotherapy in patients with MET-driven, unresectable, locally ...

CHF. 2005;11(1):30-38. Primary sites of action of B-type natriuretic peptide (BNP) in the nephron. Aldo=aldosterone; GFR=glomerular filtration rate; JGA=juxtaglomerular apparatus. Adapted with ...

Lewy body diseases (LBDs) are a class of debilitating neurodegenerative disorders linked to the abnormal aggregation of the protein α-synuclein in nerve cells. When misfolded, this protein can produce ...

Biomarker analyses in patients with advanced renal cell carcinoma (aRCC) from the phase 3 CLEAR trial. Circulating kidney injury molecule-1 (KIM-1) biomarker analysis in IMmotion010: A randomized ...

Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter ...

A CT angiogram can provide detailed imagery of the blood vessels that go into the kidneys to help diagnose renal artery stenosis. (Photo Credit: ZEPHYR/Science Source) Most of the time, renal artery ...

Renal hypertension is the most common type of secondary hypertension. It’s caused by renal (kidney) disease. Lifestyle changes and medical treatments can help manage this condition. Share on Pinterest ...

Vasoconstriction is narrowing or constriction of the blood vessels. It happens when smooth muscles in blood vessel walls tighten. This makes the blood vessel opening smaller. “Vaso” actually means ...

At the 43rd annual J.P. Morgan Healthcare Conference on Monday, Medtronic CEO Geoff Martha mixed in some breaking news with his usual pitch to investors. Just hours earlier, the Centers for Medicare ...

Patients with renal-cell carcinoma who undergo nephrectomy have no options for adjuvant therapy to reduce the risk of recurrence that have high levels of supporting evidence. In a double-blind, phase ...