Background One-size-fits-all interventions reduce chronic low back pain (CLBP) a small amount. An individualised intervention called cognitive functional therapy (CFT) was superior for CLBP compared ...

Explore the latest evidence from UNSW Sydney and NeuRA on non-drug, non-surgical treatments for acute and chronic low back pain (LBP). Based on a Cochrane review of over 97,000 participants ...

Antidepressants are prescribed for low back pain (LBP), most commonly when other treatments have failed. However, there is little consensus about what class of antidepressant works best, so ...

HealthDay News — There is some evidence for epidural steroid injections (ESIs) reducing pain and disability in cervical and lumbar radiculopathies and possibly in lumbar spinal stenosis ...

Source Reference: Armon C, et al "Epidural steroids for cervical and lumbar radicular pain and spinal stenosis: Systematic review summary report of the AAN guidelines subcommittee" Neurology 2025 ...

Background Low back pain is one of the most prevalent musculoskeletal conditions in the world. Many exercise treatment options exist but few interventions have utilised free-weight resistance training ...

Objectives Patients receiving chiropractic spinal manipulation (CSM) for low back pain (LBP) are less likely to receive any opioid prescription for subsequent pain management. However, the likelihood ...

Only in Japan is condoliase currently on the market for lumbosacral radicular pain. Since 2018, an estimated 29,000 Japanese patients have received condoliase to date, according to sponsor ...

Patients with radicular pain receiving epidural steroid injections (ESIs) are at an increased risk for osteoporotic fractures, as cited by recent study results published in the Journal of Bone and ...

Multiple systematic reviews support that epidural glucocorticoid injection can provide pain relief and improve function for up to 6 weeks. 1-5 The injection can be repeated, although the maximum ...

The investigational injection SI-6603 may decrease pain scores for patients with radicular leg pain associated with lumbar disc herniation. Two phase 3 trials were performed in the U.S. and Japan.