So the stronger the RTK response, the brighter the cell glows when viewed ... “This is a window into the dynamics of cellular signaling that we really didn't have before.” Reference: Farahani PE, Yang ...

DNA methylation, RTK pathway changes, and KRAS amplifications may drive resistance to sotorasib plus panitumumab in KRAS G12C ...

Receptor tyrosine kinases (RTKs) are a large group of integral membrane signaling molecules. Mutations in the RTK anaplastic lymphoma kinase (Alk) protein have been linked with non-Hodgkin lymphoma, ...

SOS1 is a guanine nucleotide exchange factor (GEF) that activates KRAS, and recent preclinical studies have demonstrated that combining KRAS and EGFR inhibitors with SOS1 inhibitors can overcome ...

ComNav Technology has introduced the Jupiter Laser RTK, which is designed for surveying and stakeout operations. The system offers a range of up to 50 m with centimeter-level accuracy and eliminates ...