While those of us in the film and video industry in the United States might still be pretty depressed about how the tariff ...

DNA methylation, RTK pathway changes, and KRAS amplifications may drive resistance to sotorasib plus panitumumab in KRAS G12C ...

The data will be of interest to scientists working in vascular biology and RTK signaling. The molecular mechanisms that drive (lymph-)angiogenesis are crucial to understand diseases, such as ...

The highly successful research program in the Wang laboratory focuses on the structure, signaling, functions and therapeutic targeting of Eph family receptor tyrosine kinases (RTK) in cancer. The 14 ...

Forecasting anything five years from now is foolhardy, especially so in college athletics. Four years and 51 weeks ago, the entire world shut down and took March Madness with it, a traumatic turn ...

Taken together, these results show that information processing by RTKs can be segmented into discrete upstream and downstream steps, suggesting that the challenging task of constructing mathematical ...

Functionally, SUMOylation facilitated HEY1-mediated suppression of angiogenic RTK (receptor tyrosine kinase) signaling and angiogenesis in primary human endothelial cells and mice with endothelial ...

Lovastatin also has a beneficial antitumor effect by inhibiting several other signaling pathways. These include the transmembrane RTK, MAPK, EGF, TGFβ, and insulin receptor signaling pathways, ...

Receptor tyrosine kinases (RTKs) are major signaling hubs in metazoans, playing crucial roles in cell proliferation, migration, and differentiation. However, few tools are available to measure the ...