Cancer researchers have discovered something remarkable hiding in plain sight: a common bacteria used to make sauerkraut and ...

Zhuoran Qiao has been awarded the inaugural Chen Institute and Science Prize for Al Accelerated Research for work critical to ...

This study reports the important development and characterization of next-generation analogs of the molecule AA263, which was previously identified for its ability to promote adaptive ER proteostasis ...

Background The elimination of HBV covalently closed circular DNA (cccDNA) remains a critical hurdle for chronic hepatitis B (CHB) management. Objective In this investigation, we examined the efficacy ...

While AI-driven approaches tout increased speed and lower costs, commercial interests compromise scientific collaboration.

Perhaps best known as a immune-system boost or antidote to scurvy, vitamin C has been found to rejuvenate aging skin by ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

In this work, the researchers showed how water molecules near a protein surface can influence misfolding. A mutation that is related to tauopathies has a subtle effect on water's dynamic structure in ...

Evogene Ltd. has unveiled a first-in-class generative AI foundation model for small-molecule design, marking a breakthrough in how new compounds are discovered. Announced on June 10, 2025, in ...

Evogene Ltd. has unveiled a first-in-class generative AI foundation model for small-molecule design, marking a breakthrough in how new compounds are discovered. Announced on June 10, 2025, in ...

As pointed out by Wargamer, the creation of this monstrous Strahd's-castle-like-but-legally-distinct model itself was crowdfunded by a 3D print designer back in November of last year.

3D generative models have shown great potential in structure-based drug design for generating ligands tailored to specific protein binding pockets. However, existing methods primarily emphasize ligand ...