An AI approach developed by researchers from the University of Sheffield and AstraZeneca, could make it easier to design ...

One of the great biological mysteries of the human body is how hundreds of complex, origami-like proteins, many of which are ...

SandboxAQ releases over 5 million AI-generated protein-drug structures to accelerate drug discovery and rival lab testing.

Scientists have created an AI approach that could make designing proteins for new medicines easier. This new AI approach ...

Scientists have developed a new machine learning framework that has shown the potential to be more accurate at inverse ...

As they are being synthesized, these nascent proteins simultaneously attempt to fold while still associated with their parent ribosome, referred to as co-translational protein folding ...

And all of that depends on the ability of the protein's string of amino acids to fold up into a complicated yet specific three-dimensional shape that enables it to function. Even so, these ...

Known as protein folding, it is one of the most complex processes in nature and, when folding goes awry, it often leads to disease. Popa's lab investigates forces affecting protein folding ...

By looking for missteps in the intricate process of folding proteins, a project at Purdue University is paving the way for a new generation of therapeutics that strike at the root of these diseases.

Edited by: James Kling K.A. Dill, S. Bromberg, K.Z. Yue, K.M. Fiebig, D.P. Yee, P.D. Thomas, H.S. Chan, "Principles of protein-folding-a perspective from simple exact ...

Protein folding raises some of biology's greatest theoretical challenges. It also lies at the root of many diseases. For example, the fundamental question of whether a protein's final tertiary ...