The term “protease inhibitor” refers to a class of medications rather than to a single medication. Specifically, they are antiviral drugs. But unlike the many, more common antiviral drugs that ...

This is why these protease inhibitor drugs are ideally used in congregate living situations such as long-term care facilities, workplaces, schools, prisons, and family homes. Once an infection is ...

Protease inhibitors are one type of antiretroviral drug used to treat HIV. Their goal is to reduce the amount of HIV virus in the body to levels that are undetectable. That said, protease ...

A volume of 5 ml blood per sample was collected in a Vacutainer tube containing K 3 EDTA (Greimer Bio-one, Kremsmuenster, Germany) as anticoagulant and the protease inhibitor Trasylol (aprotinin ...

It is necessary to elucidate the structure of this enzyme in order to develop or identify an effective inhibitor. The main protease is a cysteine protease with considerable homology to the ...

some patients do not respond to protease inhibitor therapy. For most patients, the lack of response is not due to mutation of the HIV-1 protease. In this issue of the Journal of Clinical ...

Over the seven years of the study, the percentage of samples with resistance to a protease inhibitor fell by half. A marked fall was also observed in the proportion of samples with resistance to drugs ...

Switching from a boosted protease inhibitor to the integrase inhibitor dolutegravir was associated with lipid reductions in people with HIV at higher risk of heart disease, according to results of the ...

Intermune added that Roche will exclusively license ITMN-191, and have the right to exclusively license further HCV protease inhibitor development candidates resulting from the collaboration.