A new study reveals that neurons in the brainstem respond very differently to acute versus chronic pain, potentially ...

A new study reveals that when we experience short-term (acute) pain, the brain has a built‑in way to dial down pain ...

Bogong moths use stars and Earth’s magnetic field to navigate epic migrations - revealing the first known stellar compass in ...

Billions of nocturnal Bogong moths migrate up to 1,000 km to cool caves in the Australian Alps that they have never ...

Imagine traveling more than 600 miles from the only home you’ve ever known, to a mountain ridge you’ve never been to. It’s ...

A threatened Australian insect joins the exclusive club of celestial navigators.

The first signs of Alzheimer's could hit decades before patients notice memory loss, experts have warned in a bombshell new ...

Here’s our first roster projection of spring training: Lineup • Jasson Domínguez, LF • Aaron Judge, RF • Cody Bellinger, CF • Paul Goldschmidt, 1B • Jazz Chisholm Jr., 2B ...

Starting with iPSCs, they coaxed the cells to differentiate into medium spiny neurons, aka striatal projection neurons. They are among the first to degenerate in HD, and are a hotspot for somatic CAG ...

Study uncovers how gradual CAG repeat expansion in neurons drives the onset of Huntington’s disease, offering new insights for potential therapeutic interventions. Study: Long somatic DNA-repeat ...

Expansion from 40 to 150 CAGs had no apparent effect, but striatal projection neurons with 150 to 500 or more CAGs degenerated quickly and died.

Having a gene with 40 or more CAG repeats leads to HD around middle age, when nerve cells called striatal projection neurons (SPNs) begin to die. This initiates a range of movement and cognitive ...