Researchers have made a major breakthrough in our understanding of Huntington's disease. This genetic disorder has long been known to be caused .. | Genetics And Genomics ...

but specific neurons thought to be the first to die in the course of Huntington’s — striatal projection neurons — had accumulated vastly more repeats by the time of death. Up to 98% had ...

A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over time but doesn't start causing harm until it hits a toxic threshold that ...

A recent study published in Cell reveals that the repeated DNA sequence that leads to Huntington’s disease (HD) expands ...

By crafting an artificial brain-like environment with microscopic nanopillars, researchers have successfully guided neurons to grow in structured networks. This innovation could revolutionize how scie ...

Their analysis confirmed that only striatal projection neurons—the cells primarily affected in the disease—develop significant CAG repeats. Furthermore, once the gene in a given cell reaches ...

The new model provides new insights into how neurons form networks, as well as a novel tool to understand in future how this ...

My initial hypothesis was that the nucleus accumbens projection MCH neurons would drive strong baseline food intake, but that did not end up being the case.” Interestingly, the researchers also ...