The problem is that most vector production technologies and methods were developed for the lab, rather than to support industrial supply, according to Michela Gentile, PhD, cell line manager at ...

Human embryonic kidney (HEK293) cells are the most commonly used cell line to produce viral vectors for gene therapy. Due to the complexity of their production and purification, viral vectors can be ...

The company has developed a cell line based on BHK-21 that it transformed with a plasmid containing the E1 gene of adenovirus. The data show rAAV production with this cell line, Agathos BHK-[wt E1 ...