Abnormal kinase signaling can promote other harmful traits, such as neuroinflammation and neuronal cell death. On the other ...

Alan Diehl Cell cycle regulation and ubiquitin-dependent protein degradation; integrated stress response and ncRNAs in regulation ... Yee Structure-function studies of enzymes and prion proteins using ...

This "mini prion" induces misfolding in normal tau, and its behavior is influenced by water structure around the protein, particularly by the P301L mutation. These findings may aid in developing ...

Researchers designed a synthetic fragment of the tau protein that exhibits prion-like behavior. Misfolded tau proteins are the hallmark of many neurodegenerative diseases, including Alzheimer's ...

Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The “mini prion” folds and ...

The ‘Molecular Devils’ That Cause the Most Fatal Diseases Ever Known CJD and similar brain diseases are caused by a misfolded version of the naturally occurring prion protein. When these rogue ...

Stress impacts health. Fatigue, aches, and emotional numbness are key indicators. Forgetfulness and junk food cravings also signal stress. Ignoring these signs leads to serious health issues.