“Previously Alzheimer’s research has been stuck looking at collateral damage in the form of misfolded, dead proteins that form plaques and tangles. Now it turns out that it is prion activity that ...

While there have been extensive studies of these plaques and tangles in the brains of people with Alzheimer’s, it can be challenging to discern which changes in the brain are from old age and which ...

Neuropathological examination during end-stage disease showed the deposition of prion protein in the form of frequent cortical amyloid plaques, cerebral amyloid angiopathy, and tauopathy.

Sponsor Message Strittmatter says there's no evidence the prion proteins fold into an abnormal shape or actually cause Alzheimer's. Instead, they seem to interact with early stage plaques in the ...

These plaques are a hallmark of the disease ... and it’s a familiar one – the prion protein. Incorrectly folded versions of this protein (PrPSC) are the culprits behind diseases like CJD ...

“Aβ plaques and tau NFTs are considered a common ... which changes in the brain are from old age and which are from prion activity, noted Prusiner, director of the UCSF Institute for ...

When prion proteins begin to fold abnormally and clump together — called amyloid plaques — it leads to brain damage. Disease-causing prions can transmit in various ways, for example ...

Prion-like proteins can propagate across species, potentially contributing to disease. Here the gut microbiome was analyzed ...

Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The "mini prion" folds and stacks ...

Mark Zabel: Prion diseases belong to a larger family of diseases that we refer to as protein misfolding diseases. These are diseases that also are caused by normal proteins that we all express that ...

While there have been extensive studies of these plaques and tangles in the brains of people with Alzheimer’s, it can be challenging to discern which changes in the brain are from old age and which ...